Article
Associations between hyperglycaemia and somatic transversion mutations in mitochondrial DNA of people with diabetes mellitus.
Diabetologia - 1 Nov 2003
Kamiya J, Aoki Y
Abstract excerpt
AIMS/HYPOTHESIS: Considering that increased oxidative stress induced by hyperglycaemia plays a possible role in the pathogenesis of diabetic complications and that mitochondrial DNA (mDNA) is thought to be more vulnerable than nuclear DNA, we investigated what somatic mutations actually occur in...
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