Article
The heteroplasmic 15059G>A mutation in the mitochondrial cytochrome b gene and essential hypertension in type 2 diabetes.
Diabetes & metabolic syndrome - 1 Jan 2000
Nikitin Alexey G, Lavrikova Elena Y, Chistiakov Dimitry A
Abstract excerpt
AIM: The long-term stress of high blood pressure levels increases the risk of a variety of macro- and microvascular complications of type 2 diabetes (T2D). The etiology of essential hypertension (EH) has been explored in depth, but the pathophysiology is multifactorial, complex, and poorly understood. Recent findings showed a role of inherited mutations in mitochondrial DNA (mtDNA) in maternally inherited forms...
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