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Article

The heteroplasmic m.14709T>C mutation in the tRNA(Glu) gene in two Tunisian families with mitochondrial diabetes.

Journal of diabetes and its complications - 1 Jan 2000

Mezghani Najla, Mkaouar-Rebai Emna, Mnif Mouna, Charfi Nadia, Rekik Nabila, Youssef Saoussan, Abid Mohamed, Fakhfakh Faiza

Abstract excerpt

UNLABELLED: Diabetes mellitus (DM) is a heterogeneous disorder characterized by the presence of chronic hyperglycemia. Genetic factors play an important role in the development of this disorder, and several studies reported mutations in nuclear genes implicated in the insulin function. Besides, DM can be maternally transmitted in some families, possibly due to the maternal mitochondrial inheritance. In fact,...

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Identifiers

PMID: 20045353
DOI: 10.1016/j.jdiacomp.2009.11.002

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