Article
Activation of NF-kappaB in cells productively infected with HSV-1 depends on activated protein kinase R and plays no apparent role in blocking apoptosis.
Proceedings of the National Academy of Sciences of the United States of America - 14 Oct 2003
Taddeo Brunella, Luo Ting Rong, Zhang Weiran, Roizman Bernard
Abstract excerpt
Microarray data reported elsewhere indicated that herpes simplex virus 1 induces the up-regulation of nuclear factor kappaB (NF-kappaB)-regulated genes, including that of its inhibitor, IkappaBalpha, consistent with the reports that wild-type virus induces the activation of NF-kappaB. In this rep...
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