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Article

Systemic and cell type-specific gene expression patterns in scleroderma skin

6 Oct 2003

Abstract excerpt

We used DNA microarrays representing >12,000 human genes to characterize gene expression patterns in skin biopsies from individuals with a diagnosis of systemic sclerosis with diffuse scleroderma. We found consistent differences in the patterns of gene expression between skin biopsies from individuals with scleroderma and those from normal, unaffected individuals. The biopsies from affected individuals showed...

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PMID: 14530402
DOI: 10.1073/pnas.1635114100

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