Article
Horizons in Sjögren's syndrome genetics.
Clinical reviews in allergy & immunology - 1 Jun 2007
Williams Pamela H, Cobb Beth L, Namjou Bahram, Scofield R Hal, Sawalha Amr H, Harley John B
Abstract excerpt
Sjögren's syndrome (SS) is a complex polygenic autoimmune disorder. A few major genetic effects have been identified. Historically, HLA and non-HLA genetic associations have been reported. Recently, the HLA region continued to reveal association findings. A new susceptibility region has been suggested by a study of a D6S349 microsatellite marker. Among non-HLA studies, recent association of immunoglobulin kappa...
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