Article
Saquinavir induces stable and functional expression of the multidrug transporter P-glycoprotein in human CD4 T-lymphoblastoid CEMrev cells.
HIV medicine - 1 Oct 2003
Dupuis M L, Flego M, Molinari A, Cianfriglia M
Abstract excerpt
BACKGROUND: The multidrug transporter P-glycoprotein (P-gp) is expressed in HIV-1 target cells, in a range of pharmacological barriers and in AIDS-associated tumours. P-gp substrates include HIV-1 protease inhibitors (PIs) and anticancer drugs, which are efficiently effluxed from multidrug-resist...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
