Article
P-glycoprotein in blood CD4 cells of HIV-1-infected patients treated with protease inhibitors.
HIV medicine - 1 Jan 2003
Bossi P, Legrand O, Faussat A-M, Legrand M, Bricaire F, Marie J-P, Agut H, Diquet B, Katlama C, Huraux J-M, Calvez V
Abstract excerpt
OBJECTIVE: Many factors are involved in the virological failure of antiretroviral treatments such as low pharmacological plasma levels of drugs, poor adherence to therapy and emergence of viral resistance. P-glycoprotein (P-gp) has been demonstrated to play a role in multidrug resistance in the t...
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