Article
Genetic heterogeneity of hepatitis C virus (HCV) in clinical strains of HIV positive and HIV negative patients chronically infected with HCV genotype 3a.
Journal of biological regulators and homeostatic agents - 1 Jan 2000
Bagaglio S, Bruno R, Lodrini S, De Mitri M S, Andreone P, Loggi E, Galli L, Lazzarin A, Morsica G
Abstract excerpt
The clinical correlation between the degree of HCV variability and the response to anti-HCV treatment in HIV positive patients infected with HCV genotype 3a is unknown. In this study, 27 HIV positive and 5 HIV negative patients with HCV genotype 3a infection were treated with interferon-alpha-2b with or without ribavirin. Nine patients (5 HIV positive) achieved a sustained virological response (SR) and 23 (only...
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