Article
Intracellular expression of a functional short peptide confers resistance to apoptosis.
Experimental cell research - 15 Oct 2003
Matza-Porges Sigal, Tavor Einat, Panet Amos, Honigman Alik
Abstract excerpt
Expression of free short peptides could potentially be used to modulate biochemical cascades and consequently to change cellular phenotypes. Here we demonstrate that expression of a short peptide of 15 amino acids, including the pseudo-substrate site of the baculovirus-apoptosis inhibitor P35, Asp-Gln-Met-Asp (DQMD), leads to abrogation of the apoptotic cascade. Treatment of cells, expressing the DQMD peptide...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
