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Article

Evaluation of anti-tumor property of specific and non-specific BRMs in experimental gioma by assessing the microglial cell functional and phenotypic modulations.

Cancer biology & therapy - 1 Jan 2000

Begum Zarina, Sarkar Susobhan, Mukherjee Joydeep, Ghosh Anirban, Chaudhuri Samares, Chaudhuri Swapna

Abstract excerpt

BACKGROUND: Microglial cells are considered to be the chief immunomodulatory cells of the brain. These cells play a crucial role against various neurodegenerative diseases. When modulated microglia have been shown to exert a potential anti-tumor immune response against brain neoplasms. Although several specific BRMs like IL-2, IFNgamma have been shown to modulate the microglia to get an effective anti-tumor...

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PMID: 14508105
DOI: 10.4161/cbt.2.4.423

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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