Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In Vitro and in Vivo Interactions of Homocysteine with Human Plasma Transthyretin

1 Dec 2003

Abstract excerpt

Hyperhomocysteinemia is an independent risk factor for cardiovascular disease and an emerging risk factor for cognitive dysfunction and Alzheimer's disease. Greater than 70% of the homocysteine in plasma is disulfide-bonded to protein cysteine residues. The identity and functional consequences of protein homocysteinylation are just now emerging. The amyloidogenic protein transthyretin (prealbumin), as we now...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine and Purinergic Signaling
Share to Blood Coagulation and Thrombosis Mechanisms
Share to Folate and B Vitamins Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 14507924
DOI: 10.1074/jbc.m306748200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In Vitro and in Vivo Interactions of Homocysteine with Human Plasma TransthyretinPMID 14507924Read ↗

Impact of age and amyloidosis on thiol conjugation of transthyretin in hereditary transthyretin amyloidosis.Semantic proximity Read ↗

S-Homocysteinylation effects on transthyretin: worsening of cardiomyopathy onset.Semantic proximity Read ↗

Oxidation inhibits amyloid fibril formation of transthyretin.Semantic proximity Read ↗

Transthyretin monomers: a new plasma biomarker for pre-symptomatic transthyretin-related amyloidosis.Semantic proximity Read ↗

Genetic stabilization of transthyretin, cerebrovascular disease, and life expectancy.Semantic proximity Read ↗

Transthyretin Is Dysregulated in Preeclampsia, and Its Native Form Prevents the Onset of Disease in a Preclinical Mouse ModelSemantic proximity Read ↗

Cys-10 mixed disulfide modifications exacerbate transthyretin familial variant amyloidogenicity: a likely explanation for variable clinical expression of amyloidosis and the lack of pathology in C10S/V30M transgenic mice?Semantic proximity Read ↗

Protein subunit interactions and structural integrity of amyloidogenic transthyretins: evidence from electrospray mass spectrometry.Semantic proximity Read ↗

Immunoaffinity chromatographic and immunoprecipitation methods combined with mass spectrometry for characterization of circulating transthyretin.Semantic proximity Read ↗

Mutations in cystathionine beta-synthase or methylenetetrahydrofolate reductase gene increase N-homocysteinylated protein levels in humans.Semantic proximity Read ↗

Cooperative stabilization of transthyretin by clusterin and diflunisal.Semantic proximity Read ↗

Characterization of the interaction of β-amyloid with transthyretin monomers and tetramers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.