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Article

Characterization of the interaction of β-amyloid with transthyretin monomers and tetramers.

Biochemistry - 28 Sept 2010

Du Jiali, Murphy Regina M

Abstract excerpt

β-Amyloid (Aβ) is the main protein component of the amyloid plaques associated with Alzheimer's disease. Transthyretin (TTR) is a homotetramer that circulates in both blood and cerebrospinal fluid. Wild-type (wt) TTR amyloid deposits are linked to senile systemic amyloidosis, a common disease of aging, while several TTR mutants are linked to familial amyloid polyneuropathy. Several recent studies provide support...

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Source

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Identifiers

PMID: 20795734
DOI: 10.1021/bi101280t
PMCID: PMC2943652

Genes

TTR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Characterization of the interaction of β-amyloid with transthyretin monomers and tetramers.PMID 20795734Read ↗

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