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Article

Genetic stabilization of transthyretin, cerebrovascular disease, and life expectancy.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 2013

Hornstrup Louise S, Frikke-Schmidt Ruth, Nordestgaard Børge G, Tybjærg-Hansen Anne

Abstract excerpt

OBJECTIVE: Transthyretin can cause amyloidosis attributable to destabilization of transthyretin tetramers in plasma. We tested the hypothesis that genetic stabilization of transthyretin associates with reduced risk of vascular disease and increased life expectancy. APPROACH AND RESULTS: We includ...

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Identifiers

PMID: 23580146
DOI: 10.1161/ATVBAHA.113.301273

Genes

TTR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23580146-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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