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Article

Distinct K-ras mutation pattern characterizes signet ring cell colorectal carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Sept 2003

Wistuba Ignacio I, Behrens Carmen, Albores-Saavedra Jorge, Delgado Ruby, Lopez Francisco, Gazdar Adi F

Abstract excerpt

PURPOSE: Signet ring cell colorectal carcinoma (SRCCC) represents a unique, infrequent, and highly malignant variant of colorectal cancer. To understand the pathogenesis of SRCCC, we investigated its molecular abnormalities and compared them with those of the usual type of colorectal adenocarcinoma. EXPERIMENTAL DESIGN: Microdissected archival paraffin-embedded tissue from 16 SRCCCs and 27 non-SRCCCs was used to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14506148

Genes

CAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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