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Article

The Molecular Associations of Signet-Ring Cell Carcinoma in Colorectum: Meta-Analysis and System Review.

Medicina (Kaunas, Lithuania) - 21 Jun 2022

Liu Xueting, Huang Litao, Liu Menghan, Wang Zhu

Abstract excerpt

Background: Signet ring cell carcinoma (SC) accounts for 1% of total colorectal cancer (CRC) cases and is associated with aggressive behaviors, such as lymphatic invasion and distant metastases, resulting in poor prognosis. To date, there is still a lack of consensus on the genetic etiology underpinning this cancer subtype. This study aimed to clarify the molecular associations of SC by using meta-analysis and a...

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PMID: 35888555
DOI: 10.3390/medicina58070836
PMCID: PMC9324575

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