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Article

Dysregulation of Intracellular Calcium Signaling in Alzheimer's Disease

12 Jun 2018

Abstract excerpt

SIGNIFICANCE: ) hypothesis of Alzheimer's disease (AD) gains popularity. It points to new signaling pathways that may underlie AD pathogenesis. Based on calcium hypothesis, novel targets for the development of potential AD therapies are identified. Recent Advances: Recently, the key role of neuronal store-operated calcium entry (nSOCE) in the development of AD has been described. Correct regulation of nSOCE is...

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PMID: 29890840
DOI: 10.1089/ars.2018.7506

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