Article
Cerebral amyloid angiopathy: pathogenesis and effects on the ageing and Alzheimer brain.
Neurological research - 1 Sept 2003
Weller Roy O, Nicoll James A
Abstract excerpt
Cerebral amyloid angiopathy (CAA) is a feature of ageing and Alzheimer's disease (AD); it is also associated with intracerebral hemorrhage and stroke. Here, the pathogenesis of CAA and its effects on the brain are reviewed and the possible effects of CAA on therapies for Alzheimer's disease are evaluated. Tracer experiments in animals and observations on human brains suggest that peptides such as A beta are...
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