Article
Association of HIV-specific and total CD8+ T memory phenotypes in subtype C HIV-1 infection with viral set point.
Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 2009
Burgers Wendy A, Riou Catherine, Mlotshwa Mandla, Maenetje Pholo, de Assis Rosa Debra, Brenchley Jason, Mlisana Koleka, Douek Daniel C, Koup Richard, Roederer Mario, de Bruyn Guy, Karim Salim Abdool, Williamson Carolyn, Gray Clive M
Abstract excerpt
Understanding early immunological events during HIV-1 infection that may set the course of disease progression is important for identifying correlates of viral control. This study explores the association of differentiation profiles of HIV-specific and total memory CD8(+) T cells with viral set point. A cohort of 47 HIV-1-infected individuals, with differing viral set points at 12 mo, were recruited during acute...
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