Article
Hepatitis C virus-specific cytolytic T cell responses after antiviral therapy.
Clinical immunology (Orlando, Fla.) - 1 Sept 2003
Morishima Chihiro, Musey Luwy, Elizaga Marnie, Gaba Kersten, Allison Megan, Carithers Robert L, Gretch David R, McElrath M Juliana
Abstract excerpt
Antigen-specific T cells are likely to provide a critical defense against hepatitis C virus (HCV) infection. However, their detection in blood is uncommon except in persons who undergo spontaneous recovery after acute HCV infection. We postulated that virological responses after antiviral interferon-alpha therapy may be associated with enhanced cytolytic T cell immunity. Peripheral blood memory CTL responses were...
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