Article
Accelerated entry of aortic smooth muscle cells from spontaneously hypertensive rats into the S phase of the cell cycle.
Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Jul 1992
Hadrava V, Tremblay J, Sekaly R P, Hamet P
Abstract excerpt
The present study was designed to characterize the growth kinetics of the exaggerated proliferative response to mitogens of vascular smooth muscle cells from spontaneously hypertensive rats compared with cells from normotensive Wistar-Kyoto controls. Cellular DNA content, analyzed by flow cytometry, demonstrated a 4-h accelerated entry into the S phase of the cell cycle of vascular smooth muscle cells from...
Topics
- Animals
- Aorta
- Cells, Cultured
- DNA Replication
- Hypertension
- Muscle, Smooth, Vascular
- Phenotype
- Rats
- Rats, Inbred SHR
- Rats, Inbred WKY
- S Phase
