Article
Histone H3 transcription in Saccharomyces cerevisiae is controlled by multiple cell cycle activation sites and a constitutive negative regulatory element.
Molecular and cellular biology - 1 Dec 1992
Freeman K B, Karns L R, Lutz K A, Smith M M
Abstract excerpt
The promoters of the Saccharomyces cerevisiae histone H3 and H4 genes were examined for cis-acting DNA sequence elements regulating transcription and cell division cycle control. Deletion and linker disruption mutations identified two classes of regulatory elements: multiple cell cycle activation (CCA) sites and a negative regulatory site (NRS). Duplicate 19-bp CCA sites are present in both the copy I and copy II...
Topics
- Base Sequence
- Cell Cycle
- Cloning, Molecular
- DNA, Fungal
- Gene Expression Regulation, Fungal
- Histones
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- Regulatory Sequences, Nucleic Acid