Studies on the binding of the Escherichia coli MelR transcription activator protein to operator sequences at the MelAB promoter.

doi:10.1042/bj2870501

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Article

Studies on the binding of the Escherichia coli MelR transcription activator protein to operator sequences at the MelAB promoter.

The Biochemical journal - 15 Oct 1992

Caswell R, Webster C, Busby S

Abstract excerpt

Escherichia coli MelR protein binds to two sites located upstream of the melAB transcription start site. Although both sites are required for optimal melibiose-dependent expression from the melAB promoter, some MelR-dependent expression is found if the upstream site is deleted or if the spacing b...

Topics

Autoradiography
Bacterial Proteins
Base Sequence
Binding Sites
DNA Fingerprinting
DNA, Bacterial
DNA, Recombinant
DNA-Binding Proteins
Deoxyribonuclease I
Escherichia coli
Escherichia coli Proteins
Gene Expression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Melibiose

Molecular Sequence Data

Mutation

Operator Regions, Genetic

Promoter Regions, Genetic

Protein Binding

Source

Open in PubMed Open full text

Identifiers

PMID: 1445208
DOI: 10.1042/bj2870501
PMCID: PMC1133193

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1445208-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Studies on the binding of the Escherichia coli MelR transcription activator protein to operator sequences at the MelAB promoter.PMID 1445208Read ↗

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