Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence that regulatory protein MarA of Escherichia coli represses rob by steric hindrance.

Journal of bacteriology - 1 Aug 2010

McMurry Laura M, Levy Stuart B

Abstract excerpt

The MarA protein of Escherichia coli can both activate and repress the initiation of transcription, depending on the position and orientation of its degenerate 20-bp binding site ("marbox") at the promoter. For all three known repressed genes, the marbox overlaps the promoter. It has been reported that MarA represses the rob promoter via an RNA polymerase (RNAP)-DNA-MarA ternary complex. Under similar conditions,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Bacterial
Share to DNA-Binding Proteins
Share to DNA-Directed RNA Polymerases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Escherichia coli

Share to Escherichia coli Proteins

Share to Gene Expression Regulation, Bacterial

Share to Promoter Regions, Genetic

Share to Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 20453091
DOI: 10.1128/JB.00103-10
PMCID: PMC2916391

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence that regulatory protein MarA of Escherichia coli represses rob by steric hindrance.PMID 20453091Read ↗

MarA-mediated transcriptional repression of the rob promoter.Semantic proximity Read ↗

Fis, an accessorial factor for transcriptional activation of the mar (multiple antibiotic resistance) promoter of Escherichia coli in the presence of the activator MarA, SoxS, or Rob.Semantic proximity Read ↗

Characterization of MarR, the repressor of the multiple antibiotic resistance (mar) operon in Escherichia coli.Semantic proximity Read ↗

Mutational analysis of MarR, the negative regulator of marRAB expression in Escherichia coli, suggests the presence of two regions required for DNA binding.Semantic proximity Read ↗

Characterization of MarR superrepressor mutants.Semantic proximity Read ↗

Insights into the quality of DnaA boxes and their cooperativity.Semantic proximity Read ↗

marA, a regulated locus which controls expression of chromosomal multiple antibiotic resistance in Escherichia coli.Semantic proximity Read ↗

Transcription activation at the Escherichia coli melAB promoter: interactions of MelR with its DNA target site and with domain 4 of the RNA polymerase sigma subunit.Semantic proximity Read ↗

Effects of Nucleobase Amino Acids on the Binding of Rob to Its Promoter DNA: Differential Alteration of DNA Affinity and Phenotype.Semantic proximity Read ↗

In vivo interactions between gene products involved in the final stages of molybdenum cofactor biosynthesis in Escherichia coli.Semantic proximity Read ↗

Nucleotide sequence of the Escherichia coli regulatory gene mprA and construction and characterization of mprA-deficient mutants.Semantic proximity Read ↗

Mutational scanning and affinity cleavage analysis of UhpA-binding sites in the Escherichia coli uhpT promoter.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.