Article
Pivotal roles for the receiver domain in the mechanism of action of the response regulator RamR of Streptomyces coelicolor.
Journal of molecular biology - 2 Sept 2005
O'Connor Tamara J, Nodwell Justin R
Abstract excerpt
The response regulator RamR activates expression of the ramCSAB operon, the source of the morphogenetic peptide SapB, and is therefore important for morphogenesis of the bacterium Streptomyces coelicolor. Like most response regulators, RamR consists of an amino-terminal receiver domain and a carboxy-terminal DNA binding domain. Four of five highly conserved active site residues known to be important in other...
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