Article
Assessment of lineality in bipolar I linkage studies.
The American journal of psychiatry - 1 Dec 1992
Simpson S G, Folstein S E, Meyers D A, DePaulo J R
Abstract excerpt
OBJECTIVE: To assess lineality in families of bipolar I probands, the authors used direct interviews of family members to reclassify families initially categorized as unilineal by family history. METHOD: The families of 1,800 treated bipolar I probands were screened by the family history method with multiple informants. If the proband had one or more affected sibs and one apparently unaffected parent, the parents...
Topics
- Adult
- Age Factors
- Aged
- Bipolar Disorder
- Depressive Disorder
- Family
- Female
- Genetic Linkage
- Humans
- Male
- Middle Aged
- Pedigree
- Phenotype