Article
Persistent estrogen responsiveness of ras oncogene-transformed mouse mammary epithelial cells.
Steroids - 1 Jun 1992
Suto A, Bradlow H L, Wong G Y, Osborne M P, Telang N T
Abstract excerpt
Ovarian steroids are associated with the proliferation of normal as well as tumorigenically transformed mammary epithelial cells. The experiments performed in this study were designed to establish that (1) tumorigenic transformation induced by the ras oncogene is associated with alterations in estradiol biotransformation, (2) altered endocrine responsiveness persists in the fully transformed tumor cell phenotype...
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