Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Complete Deficiency of Plasminogen-Activator Inhibitor Type 1 Due to a Frame-Shift Mutation

10 Dec 1992

Abstract excerpt

THE process of plasminogen activation is considered a critical component of diverse biologic systems in humans. This reaction, which is catalyzed in vivo by tissue-type and urokinase-type plasminogen activators, results in the conversion of plasminogen to plasmin. Plasmin has an essential role in maintaining vascular patency by converting fibrin to soluble fibrin-degradation products. In addition, plasminogen...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Coagulation and Thrombosis Mechanisms
Share to Blood properties and coagulation
Share to Protease and Inhibitor Mechanisms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1435917
DOI: 10.1056/nejm199212103272406

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Complete Deficiency of Plasminogen-Activator Inhibitor Type 1 Due to a Frame-Shift MutationPMID 1435917Read ↗

A novel missense mutation D676N in the plasminogen gene causes loss of functional activity.Semantic proximity Read ↗

The story of the serpin plasminogen activator inhibitor 1: is there any need for another mutant?Semantic proximity Read ↗

Plasminogen deficiency.Semantic proximity Read ↗

[Compound heterozygous plasminogen mutations causing hereditary plasminogen deficiency: a family study and mechanistic analysis].Semantic proximity Read ↗

Tissue plasminogen activator: the biochemistry and pharmacology of variants produced by mutagenesis.Semantic proximity Read ↗

Novel plasminogen gene mutations in Turkish patients with type I plasminogen deficiency.Semantic proximity Read ↗

PlasminogenSemantic proximity Read ↗

The plasminogen activator system: biology and regulationSemantic proximity Read ↗

Human Plasminogen Activator Inhibitor-1 (PAI-1) Deficiency: Characterization of a Large Kindred With a Null Mutation in the PAI-1 GeneSemantic proximity Read ↗

Human plasminogen activator inhibitor-1 (PAI-1) deficiency: characterization of a large kindred with a null mutation in the PAI-1 gene.Semantic proximity Read ↗

Structure and function of the plasminogen/plasmin system.Semantic proximity Read ↗

[New types of plasminogen activators].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.