Article
Comparison of human and mouse T-cell receptor variable gene segment subfamilies.
Immunogenetics - 1 Jan 1995
Clark S P, Arden B, Kabelitz D, Mak T W
Abstract excerpt
Like the immunoglobulin Igh-V and Igk-V gene families, the human or mouse TCRV gene families may be grouped into subfamilies displaying > 75% nucleic acid sequence similarity among their members. Systematic interspecies sequence comparisons reveal that most mouse Tcr-V subfamilies exhibit clear homology to human TCRV subfamilies (> 60% amino acid sequence similarity). Homologous pairs of TCRV genes in mice and...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Biological Evolution
- Humans
- Mice
- Molecular Sequence Data
- Polymorphism, Genetic
- Receptors, Antigen, T-Cell, alpha-beta
- Receptors, Antigen, T-Cell, gamma-delta
- Sequence Alignment