Article
Plasminogen with type-I mutation is polymorphic in the Japanese population.
Human genetics - 1 Jan 2000
Kikuchi S, Yamanouchi Y, Li L, Kobayashi K, Ijima H, Miyazaki R, Tsuchiya S, Hamaguchi H
Abstract excerpt
A functionally inactive plasminogen (PLG) variant designated as PLG M5 is polymorphic in the Japanese population and has a feature common to PLG with type-I mutation that has a codon 601 missense mutation in exon 15 (GCT for Ala-->ACT for Thr). This study was conducted to clarify whether the type-I mutation of PLG is present in PLG M5 and polymorphic in the Japanese population. Direct sequencing of the amplified...
Topics
- Asian People
- Base Sequence
- Blotting, Western
- Exons
- Humans
- Isoelectric Focusing
- Japan
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Plasminogen
- Polymerase Chain Reaction