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Article

A novel missense mutation in two families with congenital plasminogen deficiency: identification of an Ala675 to Thr675 substitution.

Thrombosis and haemostasis - 1 Jan 1996

Mima N, Azuma H, Shigekiyo T, Saito S

Abstract excerpt

We used a polymerase chain reaction (PCR) strategy and restriction fragment polymorphism analysis to evaluate all 19 exons of the plasminogen (PLG) gene in a Japanese patient with congenital PLG deficiency and her family members (family C). Sequence analysis following amplification of each exon and its flanking regions showed a single G to A transition in exon 17, resulting in the conversion of an Ala675 codon...

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Identifiers

PMID: 8713786

Genes

PLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A novel missense mutation in two families with congenital plasminogen deficiency: identification of an Ala675 to Thr675 substitution.PMID 8713786Read ↗

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