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Article

Histidine aminotransferase activity in Streptomyces tendae and its correlation with nikkomycin production.

FEMS microbiology letters - 1 Oct 1992

Roos U, Mattern S, Schrempf H, Bormann C

Abstract excerpt

Streptomyces tendae Tü901 produces nikkomycins belonging to the nucleoside peptide antibiotics. Mutants defective in histidine catabolism were isolated and characterized with regard to their histidine ammonium-lyase activity and antibiotic synthesis. In the histidine ammonialyase-negative mutant hut-11 which was unimpaired in nikkomycin production histidine aminotransferase activity was detected as an additional...

Topics

Aminoglycosides
Anti-Bacterial Agents
Kinetics
Mutation
Pyruvates
Streptomyces
Transaminases

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1427000
DOI: 10.1016/0378-1097(92)90384-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1427000-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Histidine aminotransferase activity in Streptomyces tendae and its correlation with nikkomycin production.PMID 1427000Read ↗

Molecular characterization of co-transcribed genes from Streptomyces tendae Tü901 involved in the biosynthesis of the peptidyl moiety of the peptidyl nucleoside antibiotic nikkomycin.Semantic proximity Read ↗

Molecular characterization of co-transcribed genes from Streptomyces tendae Tü901 involved in the biosynthesis of the peptidyl moiety and assembly of the peptidyl nucleoside antibiotic nikkomycin.Semantic proximity Read ↗

Production of nikkomycins Bx and Bz by mutasynthesis with genetically engineered Streptomyces tendae Tü901.Semantic proximity Read ↗

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