Article
Phenotypic characterization of isolated intraepithelial lymphocytes in patients with ulcerative colitis and normal controls.
Digestive diseases and sciences - 1 Nov 1992
Hoang P, Senju M, Lowes J R, Jewell D P
Abstract excerpt
A method was developed to isolate colonic intraepithelial lymphocytes in patients with ulcerative colitis (N = 8) and normal controls (N = 13) in order to characterize their phenotype using a panel of monoclonal antibodies and flow cytometry. In both groups, the majority of the cells are of the CD3+CD8+ phenotype associated with cytotoxic/suppressor function. The CD4/CD8 ratios were similar. Virtually no B cells...
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