Intestinal Intraepithelial Lymphocytes Contain a CD3⁻ CD7⁺ Subset Expressing Natural Killer Markers and a Singular Pattern of Adhesion Molecules

Abstract excerpt

Intestinal intraepithelial lymphocytes (i-IEL) represent one of the largest, non-organized lymphoid population in the body. They are located outside the epithelial basement membrane among the mucosal epithelial cells. We, and previously other groups, have reported the presence of a CD7+CD3-IEL subset in the epithelium of human small intestine. This subset is drastically reduced in coeliac disease (CD) patients....

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