Two-color immunofluorescence and flow cytometric analysis of lamina propria lymphocyte subsets in ulcerative colitis and Crohn's disease.

doi:10.1007/BF01296815

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Article

Two-color immunofluorescence and flow cytometric analysis of lamina propria lymphocyte subsets in ulcerative colitis and Crohn's disease.

Digestive diseases and sciences - 1 Oct 1991

Senju M, Wu K C, Mahida Y R, Jewell D P

Abstract excerpt

By using two-color immunofluorescence with fluorescein isothiocyanate (FITC) and phycoerythrin (PE)-labelled monoclonal antibodies and multiparameter flow cytometry, we investigated lamina propria lymphocyte subsets of patients with ulcerative colitis (UC) and Crohn's disease (CD). Leu-3/Leu-2 (CD4/CD8) ratio of lamina propria lymphocytes (LPL) of CD (mean +/- SD: 1.9 +/- 0.8, P less than 0.01) was significantly...

Topics

Adolescent
Adult
Aged
Antibodies, Monoclonal
B-Lymphocyte Subsets
CD4-CD8 Ratio
Colitis, Ulcerative
Crohn Disease
Female
Flow Cytometry
Fluorescent Antibody Technique

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

In Vitro Techniques

Intestinal Mucosa

Male

Middle Aged

Phenotype

T-Lymphocyte Subsets

Source

Open in PubMed

Identifiers

PMID: 1914770
DOI: 10.1007/BF01296815

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1914770-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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