Article
Axotomized frog sciatic nerve releases diffusible neurite-promoting factors.
Brain research. Developmental brain research - 18 Sept 1992
Tedeschi B, Liuzzi F J
Abstract excerpt
Using the bullfrog (Rana catesbeiana) dorsal root ganglia (DRG) and its sciatic nerve (ScN) as a model system, we have previously described neuronal and non-neuronal molecular changes associated with the early regenerative response of DRG neurons to axotomy. Since diffusible molecular factors, released by axotomized ScN, might function to stimulate axon regrowth, we have assayed the ability of ScN-conditioned...
Topics
- Animals
- Autoradiography
- Axons
- Blotting, Western
- Electrophoresis, Polyacrylamide Gel
- Ganglia, Spinal
- Nerve Growth Factors
- Nerve Regeneration
- Neurites
- PC12 Cells
- Phenotype
- Rana catesbeiana