Article
Enhanced neurotrophin-induced axon growth in myelinated portions of the CNS in mice lacking the p75 neurotrophin receptor.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 May 1999
Walsh G S, Krol K M, Crutcher K A, Kawaja M D
Abstract excerpt
Axonal growth in the adult mammalian CNS is limited because of inhibitory influences of the glial environment and/or a lack of growth-promoting molecules. Here, we investigate whether supplementation of nerve growth factor (NGF) to the CNS during postnatal development and into adulthood can support the growth of sympathetic axons within myelinated portions of the maturing brain. We have also asked whether...
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