Article
Derived motor neurons transplantation promotes nerve regeneration in a rodent model of a chronically denervated nerve through delayed adoption of a chronic denervation phenotype
2025-01-22
Abstract excerpt
After acute injury, the peripheral nervous system regenerates more efficiently than the central nervous system, but this advantage is not maintained with chronic injuries. In large animals like humans, the slow rate of axon growth and the long distance between the central nervous system and end organ result in the adoption of a chronically denervated nerve phenotype even in the setting of acute injury: distal area...
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Identifiers and source
- Literature Corpus work
- cb70c9d1-d4c4-5fc4-ab40-747ba1ff4846
- DOI
- 10.1101/2025.01.21.634102
