Article
Schwann cells migrate along axons in the absence of GDNF signaling.
BMC neuroscience - 3 Aug 2012
Heermann Stephan, Spittau Björn, Zajzon Katalin, Schwab Markus H, Krieglstein Kerstin
Abstract excerpt
BACKGROUND: During development neural crest derived Schwann Cell (SC) precursors migrate to nerve trunks and populate nascent nerves. Axonal ensheathment by SC is a prerequisite for normal nerve function and the integrity of myelinated as well as nonmyelinated axons. To provide adequate support functions, SC colonize entire nerves. One important prerequisite for this is their migration into distal axonal regions....
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