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Article

Interactions and Feedbacks in E-Cadherin Transcriptional Regulation

28 Jun 2021

Abstract excerpt

Epithelial tissues rely on the adhesion between participating cells to retain their integrity. The transmembrane protein E-cadherin is the major protein that mediates homophilic adhesion between neighbouring cells and is, therefore, one of the critical components for epithelial integrity. E-cadherin downregulation has been described extensively as a prerequisite for epithelial-to-mesenchymal transition and is a...

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PMID: 34262912
DOI: 10.3389/fcell.2021.701175

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