Molecular analysis of human glycophorin MiIX gene shows a silent segment transfer and untemplated mutation resulting from gene conversion via sequence repeats.

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Article

Molecular analysis of human glycophorin MiIX gene shows a silent segment transfer and untemplated mutation resulting from gene conversion via sequence repeats.

Blood - 1 Nov 1992

Huang C H, Skov F, Daniels G, Tippett P, Blumenfeld O O

Abstract excerpt

The human glycophorin (HGp) loci that define the red blood cell surface antigens of the MNSs blood group system exhibit considerable allelic variation. Previous studies have identified gene conversion events involving HGpA(alpha) and HGpB(delta) that produced delta-alpha-delta hybrid genes which differ in the location of breakpoints. This report presents the molecular analysis of HGpMilX, the first example of a...

Topics

Amino Acid Sequence
Base Sequence
Blotting, Southern
DNA
Exons
Female
Gene Conversion
Genetic Variation
Glycophorins
Humans
Introns
Leukocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Molecular Sequence Data

Mutation

Pedigree

Polymerase Chain Reaction

Repetitive Sequences, Nucleic Acid

Source

Open in PubMed

Identifiers

PMID: 1421409

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1421409-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Molecular analysis of human glycophorin MiIX gene shows a silent segment transfer and untemplated mutation resulting from gene conversion via sequence repeats.PMID 1421409Read ↗

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