Article
Molecular basis for the human erythrocyte glycophorin specifying the Miltenberger class I (MiI) phenotype.
Blood - 1 Jul 1992
Huang C H, Spruell P, Moulds J J, Blumenfeld O O
Abstract excerpt
Human glycophorin Mil (HGpMil) is a structural variant of the MNSs blood group system that specifies the Miltenberger class I phenotype. We report here the molecular basis of the HGpMil gene identified in a white family in which the first homozygote was encountered. Immunoblotting analysis showed the expression of HGpMil and HGpB but the absence of HGpA on the homozygous Mil erythrocytes. Southern blot analysis...
Topics
- Amino Acid Sequence
- Base Sequence
- Blotting, Southern
- Blotting, Western
- Gene Conversion
- Genes
- Glycophorins
- Humans
- MNSs Blood-Group System
- Molecular Sequence Data
- Mutation