Molecular basis of inherited human antithrombin deficiency.

Article

Molecular basis of inherited human antithrombin deficiency.

Blood - 1 Nov 1992

Blajchman M A, Austin R C, Fernandez-Rachubinski F, Sheffield W P

Abstract excerpt

Figures 1 and 4 summarize the various AT mutations that have been described. The molecular elucidation, over the past decade, of the various AT deficiency types has provided important new insights into functional-structural relationships of AT. This knowledge, together with data provided by monoc...

Topics

Alleles
Amino Acid Sequence
Antithrombins
Binding Sites
Humans
Mutation
Thrombin

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