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Article

The molecular basis of beta-thalassemia in Thailand: application to prenatal diagnosis.

American journal of human genetics - 1 Sept 1990

Thein S L, Winichagoon P, Hesketh C, Best S, Fucharoen S, Wasi P, Weatherall D J

Abstract excerpt

To enable the prenatal diagnosis of beta-thalassemia by direct detection of the mutant beta-globin genes, we have determined the spectrum of mutations causing this disease in Thailand. The techniques employed included a combination of synthetic oligonucleotide probe hybridization, direct sequencing of genomic DNA enzymatically amplified by the polymerase chain reaction, and cloning and sequencing of the...

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Identifiers

PMID: 2393018
PMCID: PMC1683861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The molecular basis of beta-thalassemia in Thailand: application to prenatal diagnosis.PMID 2393018Read ↗

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