Article
The molecular basis of alpha-thalassemia in Thailand.
The Southeast Asian journal of tropical medicine and public health - 1 Jan 1992
Winichagoon P, Fucharoen S, Wasi P
Abstract excerpt
Alpha thalassemia is the most common single gene mutation worldwide. In Thailand there exists 15-30% alpha-thalassemia carriers distributed throughout the country. DNA analysis by Southern blot hybridization reveals that the two major alpha-thalassemia alleles, alpha-thalassemia 1 and alpha-thalassemia 2 have different extents of alpha-globin gene deletion. In alpha-thalassemia 1, approximately 20 kb of DNA...
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