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Identification of genetic susceptibility loci for insulin-dependent diabetes in Sudan.

Scandinavian journal of immunology. Supplement - 1 Jan 1992

Magzoub M M, Stephens H A, Gale E A, Franco Bottazzo G

Abstract excerpt

In this study we report, for the first time, the molecular analysis of HLA-DR and DQ gene frequencies in a large cohort of well-characterized type 1 (insulin-dependent) diabetes mellitus (IDDM) patients (n = 72), and ethnically matched controls (n = 59) collected in sub-Saharan Africa. High molecular mass DNA was prepared and analysed in Southern blots and by oligonucleotide typing. We have shown a strong...

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PMID: 1355306
DOI: 10.1111/j.1365-3083.1992.tb01649.x

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