Article
Evaluation of a cold-adapted influenza B/Texas/84 reassortant virus (CRB-87) vaccine in young children.
Journal of clinical microbiology - 1 Sept 1992
Anderson E L, Newman F K, Maassab H F, Belshe R B
Abstract excerpt
A cold-adapted (ca) influenza B reassortant virus vaccine that contained the six internal RNA segments from influenza B/Ann Arbor/1/66 ca virus and the neuraminidase and hemagglutinin genes from wild-type influenza B/Texas/1/84 virus was evaluated in children ranging in age from 8 months to 14 years. The children were vaccinated intranasally with doses ranging from 10(3.2) to 10(6.2) 50% tissue culture infective...
Topics
- Adaptation, Biological
- Adolescent
- Child
- Child, Preschool
- Cold Temperature
- Evaluation Studies as Topic
- Genetic Variation
- Humans
- Infant
- Influenza B virus
- Influenza Vaccines