DNA replication defect in Salmonella typhimurium mutants lacking the editing (epsilon) subunit of DNA polymerase III.

Abstract excerpt

In Salmonella typhimurium, dnaQ null mutants (encoding the epsilon editing subunit of DNA polymerase III [Pol III]) exhibit a severe growth defect when the genetic background is otherwise wild type. Suppression of the growth defect requires both a mutation affecting the alpha (polymerase) subunit...

Topics

• Base Sequence
• DNA Polymerase I
• DNA Polymerase III
• DNA Repair
• DNA Replication
• DNA, Single-Stranded
• Genetic Complementation Test
• Molecular Sequence Data
• Mutation
• Nucleic Acid Conformation
• RNA Editing
• Salmonella typhimurium