Article
Expression of cytokine genes, cytokine receptor genes, and transcription factors in cultured Hodgkin and Reed-Sternberg cells.
Cancer research - 15 Jun 1992
Gruss H J, Brach M A, Drexler H G, Bonifer R, Mertelsmann R H, Herrmann F
Abstract excerpt
In the present study, we show by Northern blot analysis and enzyme linked immunosorbent assay that the Hodgkin's disease (HD)-derived cell lines HDLM-2 and KM-H2 express a variety of cytokine genes either constitutively or upon induction with phorbol ester 12-O-tetradecanoylphorbol-13-acetate. Cy...
Topics
- Antigens, CD
- Base Sequence
- Cell Nucleus
- Cytokines
- Gene Expression
- Genotype
- Hodgkin Disease
- Humans
- Molecular Sequence Data
- Phenotype
- RNA, Messenger
- Reed-Sternberg Cells
- Tetradecanoylphorbol Acetate
- Tumor Cells, Cultured