Article
The predictive value of epitope analysis in highly sensitized patients awaiting renal transplantation.
Transplantation - 27 Apr 1995
Laundy G J, Bradley B A
Abstract excerpt
The accumulation of highly sensitized patients (HSP) on renal transplant waiting lists is a problem faced by all transplant registries. We have studied the HLA class I serological reactivity of 20 random HSP and have related antibody specificity to primary amino acid sequence. In six patients we...
Topics
- Antibody Specificity
- Epitopes
- Female
- Genetic Variation
- HLA-A Antigens
- HLA-B Antigens
- HLA-C Antigens
- Histocompatibility Antigens Class I
- Histocompatibility Testing
- Humans
- Immunization
- Kidney Transplantation
- Male
- Models, Structural
- Predictive Value of Tests
- Protein Structure, Secondary
- Random Allocation
- Tissue Donors
